Análisis genético del individuo de Chan do Lindeiro: caracterización de su mitogenoma y situación de la muestra en el contexto paleogenético europeo
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En este trabajo se presentan los primeros resultados de un estudio de paleogenética realizado en los restos óseos de Elba, la mujer mesolítica de Chan do Lindeiro (Pedrafita do Cebreiro, Lugo). El estudio se realizó a nivel de ADN mitocondrial completo y de marcadores nucleares relacionados con rasgos fenotípicos, como pigmentación y tolerancia a la lactosa. El método se basa en el enriquecimiento mediante captura por hibridación de ADN mitocondrial y genómico, seguido de secuenciación de alto rendimiento. La cobertura obtenida para los marcadores genómicos resultó insuficiente, pero el genoma mitocondrial se recuperó en un 99%. La mujer de Chan do Lindeiro pertenece al haplogrupo U, característico de los cazadores recolectores europeos, y dentro de éste, en el subhaplotipo U5b1, cuyo origen se sitúa en la Península Ibérica hace unos 16-20000 años.
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