Cutaneous angiomyolipoma in the foot. A case report
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Abstract
Epithelioid angiomyolipoma is a type of perivascular epithelioid cell neoplasms (PEComas) related with soft tissues. Renal angiomyolipoma is the most known type.
PEComas can appear in multiple locations such as gastrointestinal tract, genitourinary o soft tissues.
Different variants share a histologic pattern characterized by abundant thin-walled vessels surrounded by perivascular cells with clear cytoplasm.
Immunohistochemical stains reveal melanogenic markers (HMB45, Melan-A, or tyrosine) in addition to muscle markers (SMA, actin, myosin, calponin, and h-caldesmon).
However, erratic and not pathognomonic positivity united to low prevalence, complicates differential diagnosis.
We report a case of right foot cutaneous angiomyolipoma with a brief review of these tumours.
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